Phenol can cause irregular heartbeat (arrhythmia). (1,7)Phenol is very soluble in water and is quite flammable. Safe work practices should always be followed. Description. The comparative acute toxicity data for resorcinol and phenol clearly show that resorcinol is significantly less toxic than phenol which has a 5 ppm TLV. TWA: 19 mg/m³ 8 hours. Phenol is a colorless or white solid when it is pure; however, it is usually sold and used as a liquid. Phenol Vapor Monitor (OV-85) quantity. Data Sheet (eSDS). However, there are limited epidemiological evidences of the relationships between exposure to phenols and pregnancy outcomes. ... Avoid exposure. Each manufac¬turing facility should have a thorough training programme for employees and appropriate work processes and safety equipment in place to limit unnecessary exposure. “Regulated area.” Any area where concentrations of airborne benzene exceed or can reasonably be expected to exceed, the allowable employee exposure limits, either the 8-hour time-weighted average exposure limit of 1 ppm or the short-term exposure limit of … SECTION 8 : Exposure controls/personal protection Control Parameters: 108-95-2, Phenol, TWA 5.000000 ppm USA. Phenol Vapor Monitor (OV-85) $60.00. (2)The chemical formula for phenol is C6H6O and the molecular weight is 94.1 g/mol. Effects of Over Exposure: Toxicity Data: Phenol LC50 (inhalation, rat) 316 mg/m3/4hr LD50 (skin, rat) 669 mg/kg LD50 (oral, mouse) 270 mg/kg Water No information available Phenol is listed by the IARC as Group 3, Unclassifiable. Acute exposure to phenol vapor may cause severe eye and respiratory irritation. If inhaled, phenol can cause upper respiratory irritation, lung damage, and CNS impairment. Phenol is a normally found at low levels in human urine; however, a high concentration may suggest exposure to phenol within the previous one or two days. To limit exposure to phenol, a deep chemical peel is done a portion at a time, in 10- to 20-minute intervals. Biological Exposure Index (BEI): Determinant: Phenol in urine (with hydrolysis); Sampling Time: end of shift; BEI: 250 mg/g creatinine. Threshold Limit Values (TLVs) refer to airborne concentrations of chemical substances and represent conditions under which it is believed that nearly all workers may be repeatedly exposed, day after day, over a working lifetime, without adverse effects. exposure to chemicals listed by the State as causing cancer or reproductive toxicity. the urine (phenol) can estimate personal exposure. (f) Milligrams of substance per cubic meter of air at 25°C and 760mm Hg pressure. OSHA PEL (United States, 2/2013). EH40/2005 Workplace exposure limits 10 Substance CAS Workplace exposure limit Comments number Long-term exposure Short-term exposure limit (8-hour TWA limit (15-minute reference period) reference period) ppm mg.m-3 ppm mg.m-3 Acetaldehyde 75-07-0 20 37 50 92 R12, 36/37, 40 Acetic anhydride 108-24-7 0.5 2.5 2 10 R10, 20/22, 34 Dilute phenol solutions have been injected for celiac plexus nerve blocks. Occupational exposure limits Phenol ACGIH TLV (United States, 3/2015). Occupational hygiene uses methods for exposure identification and evaluation following the techniques of anticipation, identification, evaluation, and control. Workplace exposure limits (WEL) have been set in the UK, to protect workers from the harmful effects of phenol. Inhalation of phenol vapor may cause lung edema. Long-term or repeate… The phenolic mixture used classically is 3 ml of 50% phenol, 2 ml of water, 8 drops of soap and 8 drops of croton oil. Phenol, 4-(1,1-dimethylethyl)- 98-54-4 100 See Section 8 for Exposure Guidelines and Section 15 for Regulatory Classifications. Phenol chemical peel is a technique which has been used in superficial surgery of the skin for the last 30 years (Ersek, 1991). ACGIH 108-95-2 , Phenol, TWA 5.000000 ppm 19.000000 mg/m3 USA. Phenol ACGIH TLV (United States, 1/2005). Check Interaction. A chemical peel isn't for everyone. We evaluated the associations between parental urinary levels of various phenols and spontaneous … Phenol limits the signals sent from the nerves to muscles that cause muscle contractions. While concentrated phenol is very hazardous, exposure to small amounts of phenol from consumer products and foods is not expected to be hazardous. Information About Contaminants Found at Hazardous Waste Sites. Phenol is particularly toxic to the central nervous system, kidneys and liver Inhalation: Phenol is absorbed through skin and mucous membranes and will produce irritation as well as the same effects as ingestion. Use adequate ventilation to keep airborne concentrations low. * It should be recognized that Phenol, 3-(1-Methylethyl)-, Methylcarbamate can be absorbed through your skin, Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). TWA: 19 mg/m³ 10 hours. In experimental animals, phenols increased resorptions, reduced live litter size and fetal body weights. ACGIH A4: Not classifiable as a human carcinogen (Phenol). The maximum daily total deposition of 44.5 mg phenol/m 2 and the maximum 24-hour concentration of phenol in air of 0.022 mg phenol/m 3 were used in the hyperconservative assessment to estimate exposure in the field nearest to Company 1. Phenol 108-95-2 Hazard Summary Exposure to phenol may occur from the use of some medicinal products (including throat lozenges and ointments). Phenol is highly irritating to the skin, eyes, and mucous membranes in humans after acute (short-term) inhalation or dermal exposures. Phenol is considered to be quite toxic to humans via oral exposure. WEL – workplace exposure limit, LTEL – long-term exposure limit, STEL – short-term exposure limit Reference Health and Safety Executive (HSE). 7.2 Specific Restrictions The European Community legislation stipulates that phenol and its alkali salts must not be contained in cosmetic products, except when subject to certain restrictions and conditions laid down. Its corrosive effect on skin and mucous membranes is due to a protein-degenerating effect. Workplace Exposure Limits OSHA: The legal airborne permissible exposure limit (PEL) is 50 ppm, not to be exceeded at any time. SECTION 8: Exposure Controls/personal protection 8.1. 3 Effective date : 10.24.2014 Page 2 of 6 Phenol Red Indicator Solution, 0.02% w/v Created by Global Safety Management, 1-813-435-5161 - www.GSMSDS.com Occupational exposure levels are generally reported to be less than 1 ppm (4 mg/m3), although levels up to 4.4 ppm (17 mg/m3) have been reported in a plant manufacturing synthetic fibres. Phenol burns and intoxications can be life-threatening. NIOSH: The recommended airborne exposure limit (REL) is 5 ppm averaged over a 10-hour workshift and Exposure Controls/Personal Protection OSHA Permissible Exposure Limits (PELs): Reagent CAS # OSHA PEL TWA Phenol 108-95-2 5 ppm (19 mg/m3) [skin] ACGIH Threshold Limit Values (TLVs): Reagent CAS # ACGIH PEL TLV ACGIH STEL Engineering Controls: Use in a well ventilated area to prevent exposure. Phenol is highly irritating to the skin, eyes, and mucous membranes in humans after acute (short-term) inhalation or dermal exposures. The goal is to identify solutions for eliminating or reducing the hazard, and monitoring to ensure no further harm occurs. The ATSDR Public Health Statements (PHSs) listed below are a series of summaries about hazardous substances developed by the ATSDR Division of Toxicology. Repeated or prolonged skin contact with phenol may cause dermatitis, or even second and third-degree burns. The 8-hour inhalation (rat) LC0 is 900 mg/m3. EC Inventory, Pre-Registration process, Other . The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. High or repeated exposure can damage the liver, kidneys and nervous system.
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